Epidemiology Journal Club: Vaccination and Autism, Pt 3

Event Date: 
Friday, September 22, 2017 - 10:00am to 11:00am
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Continued discussion from Pts 1 and 2.  Students presented summaries of the following studies:

Bibliography: Roseman Vaccine/Autism Journal Club

1.    Wakefield, A. et al. RETRACTED: Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet 351, 637–641 (1998).

2.     Taylor, B. et al. Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association.[comment]. Lancet 353, 2026–2029 (1999).

3.      Farrington, C. P., Miller, E. & Taylor, B. MMR and autism: Further evidence against a causal association. Vaccine 19,3632–3635 (2001).

4.      Kaye, J. A., del Mar Melero-Montes, M. & Jick, H. Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners: a time trend analysis. BMJ 322, 460–3 (2001).

5.      Dales, L., Hammer, S. J. & Smith, N. J. Time Trends in Autism and in MMR Immunization Coverage in California. Jama285, 1183 (2001).

6.      Meldgaard-Madsen, K. et al. A population-based study of measles, mumps, and rubells vaccination and autism. N. Engl. J. Med. 347, 1477–1482 (2002).

7.      Hviid, A. Association Between Thimerosal-Containing Vaccine and Autism. Jama 290, 1763 (2003).

8.      Miller, E. Measles-Mumps-Rubella Vaccine and the Development of Autism. Pediatr. Infect. Dis. 14, 199–206 (2003).

9.      Verstraeten, T. et al. Safety of thimerosal-containing vaccines: a two-phased study of computerized health maintenance organization databases. Pediatrics 112, 1039–1048 (2003).

10.    Madsen, K. M. et al. Thimerosal and the occurrence of autism: negative ecological evidence from Danish population-based data. Pediatrics 112, 604–6 (2003).

11.     Geier, D. a & Geier, M. R. A comparative evaluation of the effects of MMR immunization and mercury doses from thimerosal-containing childhood vaccines on the population prevalence of autism. Med. Sci. Monit. Int. Med. J. Exp. Clin. Res. 10, PI33-I39 (2004).

12.     Horton, R., Murch, S., Anthony, A. & al.,  et. A statement by the editors of The Lancet. Lancet (London, England) 363,820–1 (2004).

13.     DeStefano, F., Bhasin, T. K., Thompson, W. W., Yeargin-Allsopp, M. & Boyle, C. Age at first measles-mumps-rubella vaccination in children with autism and school-matched control subjects: a population-based study in metropolitan atlanta. Pediatrics 113, 259–66 (2004).

14.     Smeeth, L. et al. MMR vaccination and pervasive developmental disorders: a case control study. Lancet 364, 963–969 (2004).

15.     Chen, W., Landau, S., Sham, P. & Fombonne, E. No evidence for links between autism, MMR and measles virus.Psychol. Med. 34, 543–553 (2004).

16.     Andrews, N. et al. Thimerosal Exposure in Infants and Developmental Disorders: A Retrospective Cohort Study in the United Kingdom Does Not Support a Causal Association. Pediatrics 114, 584–591 (2004).

17.     Honda, H., Shimizu, Y. & Rutter, M. No effect of MMR withdrawal on the incidence of autism: A total population study.J. Child Psychol. Psychiatry Allied Discip. 46, 572–579 (2005).

18.        Geier, D. A. & Geier, M. R. An evaluation of the effects of thimerosal on neurodevelopmental disorders reported following DTP and Hib vaccines in comparison to DTPH vaccine in the United States. J. Toxicol. Environ. Health. A 69,1481–1495 (2006).

19.     Richler, J. et al. Is there a ‘regressive phenotype’ of autism spectrum disorder associated with the measles-mumps-rubella vaccine? A CPEA study. J. Autism Dev. Disord. 36, 299–316 (2006).

20.     Fombonne, E., Zakarian, R., Bennett, A., Meng, L. & McLean-Heywood, D. Pervasive Developmental Disorders in Montreal, Quebec, Canada: Prevalence and Links With Immunizations. Pediatrics 118, e139-150 (2006).

21.     Uchiyama, T., Kurosawa, M. & Inaba, Y. MMR-vaccine and regression in autism spectrum disorders: Negative results presented from Japan. J. Autism Dev. Disord. 37, 210–217 (2007).

22.     Schechter, R. & Grether, J. K. Continuing increases in autism reported to California’s developmental services system: mercury in retrograde. Arch. Gen. Psychiatry 65, 19–24 (2008).

23.     Hornig, M. et al. Lack of association between measles virus vaccine and autism with enteropathy: A case-control study. PLoS One 3, 1–8 (2008).

24.     Young, H. A., Geier, D. A. & Geier, M. R. Thimerosal exposure in infants and neurodevelopmental disorders: An assessment of computerized medical records in the Vaccine Safety Datalink. J. Neurol. Sci. 271, 110–118 (2008).

25.     Gallagher, C. M. & Goodman, M. S. Hepatitis B Vaccination of Male Neonates and Autism Diagnosis, NHIS 1997–2002.J. Toxicol. Environ. Heal. Part A 73, 1665–1677 (2010).

26.     Mrozek-Budzyn, D., Kiełtyka, A. & Majewska, R. Lack of association between measles-mumps-rubella vaccination and autism in children: a case-control study. Pediatr. Infect. Dis. J. 29, 397–400 (2010).

27.     Price, C. S. et al. Prenatal and Infant Exposure to Thimerosal From Vaccines and Immunoglobulins and Risk of Autism.Pediatrics 126, 656–664 (2010).

28.     Hodgson, H., Murch, S., Anthony, A. & al.,  et. Retraction--Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet (London, England) 375, 445 (2010).

29.     DeLong, G. A Positive Association found between Autism Prevalence and Childhood Vaccination uptake across the U.S. Population. J. Toxicol. Environ. Heal. Part A 74, 903–916 (2011).

30.     Holland, M., Conte, L., Krakow, R. & Colin, L. Unanswered questions from the Vaccine Injury Compensation Program: A Review of Compensated Cases of Vaccine- Induced Brain Injury. Pace Environ. Law Rev. 28, (2011).

31.     Uno, Y., Uchiyama, T., Kurosawa, M., Aleksic, B. & Ozaki, N. The combined measles, mumps, and rubella vaccines and the total number of vaccines are not associated with development of autism spectrum disorder: The first case-control study in Asia. Vaccine 30, 4292–4298 (2012).

32.     Geier, D. A. et al. A two-phase study evaluating the relationship between Thimerosal-containing vaccine administration and the risk for an autism spectrum disorder diagnosis in the United States. Transl. Neurodegener. 2, 25 (2013).

33.     Centers for Disease Control and Prevention. CDC Statement Regarding 2004 Pediatrics Article ‘Age at First Measles-Mumps-Rubella Vaccination in Children With Autism and School-matched Control Subjects: A Population-Based Study in Metropolitan Atlanta’. (2014). Available at: https://www.cdc.gov/vaccinesafety/concerns/autism/cdc2004pediatrics.html. (Accessed: 18th August 2017)

34.     Destefano, F., Price, C. S. & Weintraub, E. S. Increasing exposure to antibody-stimulating proteins and polysaccharides in vaccines is not associated with risk of autism. Pediatr. Pol. 89, T31–T38 (2014).

35.     Crosby, J. Lancet keeps Wakefield et al. retracted in contempt of court. Autism Investigated 11, (2014).

36.     Hooker, B. S. Measles-mumps-rubella vaccination timing and autism among young african american boys: a reanalysis of CDC data. Transl. Neurodegener. 3, 16 (2014).

37.     Hooker, B. S. Retraction: Measles-mumps-rubella vaccination timing and autism among young African American boys: a reanalysis of CDC data. Transl. Neurodegener. 3, 22 (2014).

38.     Taylor, L. E., Swerdfeger, A. L. & Eslick, G. D. Vaccines are not associated with autism: An evidence-based meta-analysis of case-control and cohort studies. Vaccine 32, 3623–3629 (2014).

39.     Jain, A. et al. Autism occurrence by MMR vaccine status among US children with older siblings with and without autism. Jama 313, 1534–40 (2015).

40.     Uno, Y., Uchiyama, T., Kurosawa, M., Aleksic, B. & Ozaki, N. Early exposure to the combined measles-mumps-rubella vaccine and thimerosal-containing vaccines and risk of autism spectrum disorder. Vaccine 33, 2511–2516 (2015).

41.     Kern, J. CRITIQUE- Early exposure to the combined measles–mumps–rubella vaccine and thimerosal-containing vaccines and risk of autism spectrum disorder. PubMed Commons (2015). doi:10.1016/j.vaccine.2014.12.036

42.     Vaccine Papers. Jain, 2015: Autism occurrence by MMR vaccine status among US children with older siblings with and without autism. Vaccine Papers (2015). Available at: http://vaccinepapers.org/review-of-jain-et-al-jama-2015-and-comments-on-mmr-autism/. (Accessed: 18th August 2017)

43.     Hooker, B. S. Dr. Brian Hooker’s official statement regarding William Thompson. Focus For Health (2016). Available at: https://www.focusforhealth.org/dr-brian-hooker-statement-william-thompson/. (Accessed: 18th August 2017)

44.     Meltzer, A. & Van de Water, J. The Role of the Immune System in Autism Spectrum Disorder.Neuropsychopharmacology 1 (2016). doi:10.1038/npp.2016.158

45.     Zerbo, O. et al. Association Between Influenza Infection and Vaccination During Pregnancy and Risk of Autism Spectrum Disorder. JAMA Pediatr. 171, e163609 (2017).

46.     Snopes.com. Fraud at the CDC Uncovered? Snopes Available at: http://www.snopes.com/medical/disease/cdcwhistleblower.asp. (Accessed: 18th August 2017)